Tap into the vast power that you never knew you had. Open your mind to the knowledge that not just one, but all heroes can bring into your life. Only when you understand the reality that no hero stands alone, can you truly defeat the greatest enemies. Who are these greatest enemies, and why do you need this power to defeat them? Wait for someone smarter than me to write that guide. Until then you can try to enjoy this one.
All synergies happen at levels 25 and 50 of the hero in question, so you don't have to fully commit to a hero if you have a fear of that kind of thing.
Ant-Man-[+5 Credit Find / +1 Strength] All Physical heroes need this synergy. No questions.
Black Panther-[+3% Move Speed / +2% Melee Damage] Melee damage is fine, but low end. Not fit for a King. Avoid.
Black Widow-[+2% Damage to Not Targeting You / +2% Damage to Not Targeting You] Not every operation is about stealth. Situational.
Blade-[+HP on Hit / +3% Attack Speed] Just like Blade, you're only getting half the power here. OK for leveling.
Cable-[+1% Crit Chance / +1% Crit Chance] You don't need a man from the future to tell you this is a must have or all heroes.
Captain America-[+2% Total Deflection / +2% Total Deflection] You probably don't have a shield, but you should block this. Avoid.
Colossus-[+3% Base Health / +2% Physical Damage] A solid choice from a solid man, but there are better options.
Cyclops-[+2% Energy Damage / +10% Experience Gain] Widely recognized as one of the first to get, as it makes leveling that much easier.
Daredevil-[+3% Damage to Normal/Elite Enemies / +2% Melee Damage] Solid for leveling, but loses out once you leave the streets.
Deadpool-[+10% Rare Item Find / +10% Special Item Find] I hope you practice dark arts, even if it won't help you get loot with this.
Doctor Doom-[+5% Signature Damage / +5% Signature Damage] Big numbers right? It's an illuuuuusion! Poor results in practice.
Doctor Strange-[+2% Mental Damage / +2% Mental Damage] You'd have to be mental not to...not take this. A must for Mental heroes.
Emma Frost-[+3% Damage Over Time / +1 Durability] Like Emma herself, a perfect balance. If you rely heavily on DoTs and need a defense boost take this.
Gambit-[+5 Credit Find / +10% Rare Item Find] Deadpool part 2, Sleazy Cajun Boogaloo.
Ghost Rider-[+2% Mental Crit Chance / +2% Mental Crit Chance] Look into his eyes and see your sins for not taking this on a Mental hero.
Hawkeye-[+2% Move Speed / +4% Crit Damage] It's a good all arounder, but loses to straight damage nodes.
Hulk-[+3% Base Health / +3% Base Health] Hulk smashed this one a little too hard. Nothing left to see here.
Human Torch-[+2.5% Area Damage / +2.5% Area Damage] If your hero is mainly area, this is excellent. Magneto, Jean, etc.
Iceman-[+15 Spirit / +5% Damage to Slowed] If you can land slows consistently, this is great for leveling. Endgame is questionable.
Invisible Woman-[+2% Energy Damage / +2% Total Deflection] This one might as well be invisible.....I'll just leave(this one alone!)
Iron Fist-[+3% Mental Damage / +15% Health Regen per Minute] Dip your hands in this Dragon's heart to receive it's power. Excellent for mental damage heroes.
Iron Man-[+2% Range Damage / +2% Energy Damage] Zeus would be proud. Excellent for heroes like Storm, Magneto, etc.
Jean Grey-[+3% Mental Damage / +3% Energy Damage] Not a bad choice for a Mental/Energy hybrid...which doesn't really exist anymore.
Juggernaut-[+3% Movement Power Damage / +3% Movement Power Damage] Selfish guy. Benefits him immensely.
Kitty Pryde-[+2% Total Dodge / +2% Total Deflection] This one is just a phase....I promise my jokes are all this bad. Don't take it.
Loki-[+5% Damage to Slowed Targets / -5% Spirit Cost to Powers] Solid if you're hurting for spirit, and if you can apply slow it's even better.
Luke Cage-[+2% Defense / +2% Physical Damage] Not bad for a Physical hero, but it's outclassed elsewhere.
Magik-[+HP on Hit / +5% Summon Damage] Limbo or not, if you summon this is for you.
Magneto-[+4% Area Damage / +10% Orb Pickup Radius] Human Torch cooked it right, so Magneto cut off a slice. Use for Area heroes.
Moon Knight-[+2% Physical Crit / +2% Physical Crit] Another personality telling you to ditch this? He must not do Physical damage. Use it.
Mr. Fantastic-[-5% Crafting Costs / +4% Crit Damage] Great when you're rerolling an artifact, and it's good enough to leave on if you're lazy.
Ms. Marvel-[+2% Energy Damage / +2% Energy Damage] I'm pretty sure she's known for punching people, but this is a must for pure Energy.
Comments
Nova-[+3% Move Speed / +2% Total Dodge] Looks like the Cancerverse got to his brain. He forgot to add usefulness to this one.
Psylocke-[+3% Mental Damage / +3% Physical Damage] The synergy of choice for telekinetic ninjas. Also good for Emma and Ghost Rider.
Punisher-[+HP on Enemy Defeat / +Spirit on Enemy Defeat] If you're full of holes and bleeding out, you should pick this up while leveling.
Rocket Raccoon-[+5% Summon Damage / +5% Summon HP] He may not be a great pet, but your real pets will love him. Summoners.
Rogue-[+HP on Hit / +Spirit on Hit] She may steal your heart, and your mind, and.. where was I going with this? Forget this one too.
Scarlet Witch-[+2% DoT Damage / +2% DoT Damage] Finding the probability of usefulness will drive you to madness. OK for DoT builds.
She-Hulk-[+3% Physical Damage / +15% Health Regen per Minute] The court finds you guilty of usefulness. Great for Physical heroes.
Silver Surfer-[+3% Movement Speed / +2% Energy Damage] The Herald of Underwhelming has arrived. Pass this planet by.
Spider-Man-[+2% Total Dodge / +2% Total Dodge] Unfortunately I'm not witty enough to tell you to dodge this in a clever way.
Squirrel Girl-[+2% Damage to Bosses / +2% Damage to Bosses] Dr Doom and co. will find this annoying. Must have endgame synergy.
Star-Lord-[+2% Energy Crit / +2% Energy Crit] Energy users would be proud to be a part of this galaxy. Guard this one.
Storm-[+20 Spirit / +20 Spirit] What man builds, nature...helps? A must have for Iron Man, War Machine, Juggernaut, and ranged Vision.
Taskmaster-[+1% Total Dodge +1% Total Deflect / +1% Melee Damage +1% Crit Damage] Emulating this would be a mistake. Avoid.
Thing-[+2% Damage to Targeting You / +2% Damage to Targeting You] It's great being the center of attention, if you like eating dirt. Avoid.
Thor-[+3% Physical Damage / +3% Energy Damage] The God of Thunder decrees Physical/Energy hybrids will find this useful.
Venom-[+3% Health / +5% Damage if Under 50% HP] Only crazies like Moon Knight, Punisher, and Ghost Rider would form a relationship with this.
Vision-[+3% Range Damage / +10% Damage to Robots] Useful for overthrowing your robot overlords. Great in Ultron and Fight 1 Axis Raid.
War Machine-[+10 Spirit / +1 Fighting] Would you disobey a ranking officer? Take this one or be court martialed for criminal insolence.
Winter Soldier-[+3% Range Damage / +3% Melee Damage] The past is hazy, but the future is not. This is solid for a Melee/Range hybrid.
Wolverine-[+2% Brutal Chance / +5% Brutal Damage] You don't want to be on the wrong side of those claws. Take this one, bub.
X-23-[+2% Damage Vs Bleeding / +2% Damage Vs Bleeding] If you like making things bleed this is for you. Wolv, X23, MK, etc.